Mistusinne is a resort village in Saskatchewan, located within Census Division No. 7. It sits on the eastern shore of the Gordon McKenzie Arm of Lake Diefenbaker, within the Rural Municipality of Maple Bush No. 224.
As a resort village, Mistusinne is one of several small lakeside communities that developed along Lake Diefenbaker, the large reservoir in central Saskatchewan. Its position on the eastern shore of the Gordon McKenzie Arm places it within a region of the province known for recreational lake access.